Lungs are exposed to external oxidants from the environment as in harmful particles and smog. causing oxidative stress in the lungs and consequently respiratory ailment. The NF-E2-related factor 2 (Nrf2) is the one with transcriptional regulatory function. while its related protein Kelch-like ECH-associated protein 1 (Keap1) inhibits Nrf2 activity. http://www.getpureroutine.com/quick-grab-poise-pads-overnght-bulk-16-supply-mega-offer/